Table 1.

Reverse transcription-polymerase chain reaction results of NF-E2-related factor 2 and heme-oxygenase-1 (HO-1) in cerebral cortex and hippocampus. There was significant difference between sham group and each model group (P<0.05); expression of NF-E2-related factor 2 and heme-oxygenase-1 mRNA had significant increase in model group

Group	Nrf2 in cortex	Nrf2 in hippocampus	HO-1 in cortex	HO-1 in hippocampus
Sham	0.22±0.05	0.25±0.03	0.40±0.07	0.30±0.05
Normothermia group 15 min	0.43±0.03	0.43±0.09	0.58±0.09	0.49±0.06
Mild hypothermia before ROSC 15 min	0.49±0.03	0.47±0.06	0.76±0.08	0.61±0.06
Mild hypothermia after ROSC 15 min	0.49±0.07	0.48±0.02	0.70±0.04	0.65±0.03
Normothermia group 30 min	0.36±0.04	0.42±0.07	0.58±0.10	0.46±0.07
Mild hypothermia before ROSC 30 min	0.48±0.05	0.54±0.05	0.75±0.11	0.63±0.09
Mild hypothermia after ROSC 30 min	0.47±0.07	0.56±0.09	0.78±0.07	0.63±0.10
Normothermia group 60 min	0.34±0.05	0.39±0.05	0.64±0.06	0.48±0.09
Mild hypothermia before ROSC 60 min	0.52±0.06	0.57±0.03	0.82±0.09	0.74±0.08
Mild hypothermia after ROSC 60 min	0.48±0.04	0.45±0.06	0.75±0.07	0.62±0.08
F	14.535	8.953	9.720	12.139
P	0.000	0.000	0.000	0.000

ROSC: Restoration of spontaneous circulation. F and P are value of statistical analysis