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Riboflavin and mitochondrial pathways in MS. Riboflavin as an integral component of two coenzymes: FAD and FMN enhance availability of intracellular ATP, mitochondrial survival, and bio-energy, leading to increased responsiveness to BDNF followed by enhanced myelin production in MS. ADP=Adenosine diphosphate; ATP=Adenosine triphosphate; BDNF= Brain-derived neurotrophic factor; FAD= Flavin adenine dinucleotide; FMN= Flavin mononucleotide; NADH/NADH2= Nicotinamide adenine dinucleotide
