Table 3.

Active concentrations and IC₅₀ of the synthesized compounds on the MCF-7 cell line

Code	R1	R2	Active concentrations (μM)	Survival (%)	IC50 (μM)
14a	H	H	0.1, 1, 10, 100	86.52, 81.37, 38.25, 2.53	7.53
14b	Cl	H	1, 10, 100	66.93, 33.86, 0.00	5.60
14c	OMe	H	0.1, 1, 10, 100	66.20, 36.73, 1.43, 0.00	0.59
14d	H	Br	10, 100	74.96, 25.87	55.76
14f	OMe	Br	10, 100	70.00, 47.00	89.64
14g	H	OMe	1, 10, 100	98.74, 85.76, 44.46	87.97
14h	Cl	OMe	1, 10, 100	83.00, 48.00, 19.00	9.73
14i	OMe	OMe	0.1, 1, 10, 100	70.16, 68.00, 29.13, 2.07	5.16
	doxorubicin		0.5	59.70	3.62*

^(*)IC₅₀ of doxorubicin was reported based on reference 33