Figure 3.

Apatinib inhibited colon cell migration and invasion

(a) HCT116 and SW480 cells after the cells were treated with apatinib (0, 20, 40 μM, respectively) for 40 hr. The migrated cells were stained. (b) HCT116 and SW480 cells after the cells were treated with apatinib (0, 20, 40μM, respectively) for 40 hr. The invaded cells were stained. (c) HCT116 and SW480 cells after the cells were treated with apatinib (0, 20, 40 μM, respectively) for 48 hr. The migration index (the ratio of migration distance to total distance) was used to measure the movement ability. * represents P<0.05