Table 2.

Effect of thymoquinone (TQ) and ethanol (Et) on histopathological changes in liver and kidney tissues of rat after 4 weeks treatment. Histopathological criteria were determined semi-quantitatively from mild (+) to moderate (++) and sever (+++), n=6

Groups	Liver	Kidney
Control	normal	normal
Ethanol	severe congestion (+++), steatosis (++) and infiltration of inflammatory focal portal space (++)	severe congestion (+++), hematuria (++) and infiltration of inflammatory focal adjacent glomerular (++)
TQ (10 mg/kg)	normal	normal
Et + TQ (2.5 mg/kg)	moderate congestion (++)	moderate congestion (++)
Et + (5 mg/kg)	mild congestion (+)	mild congestion (+)
Et + TQ (10 mg/kg)	normal	normal