Supplementary Fig. 1.

(A) Progression rate vs. the disease duration for LMND patients and ALS patients. One part of the LMND patients shows progression rates similar to ALS patients where a smaller part shows lowered progression rates. (B) Correlation between LMND patients' FA values in the CST and disease duration. LMND patients with a long disease duration could show decreased FA values although they follow a slow disease progression; LMND patients with a high disease progression rate (even ALS like) could present comparatively high FA values due to a short disease duration. Mean FA values in the CST (± standard deviation) for controls are marked in blue, for ALS patients are marked in red.