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. 2017 Oct 23;18:807. doi: 10.1186/s12864-017-4215-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4. — Comparison of nose and lung microbiome following Pneumococcal Inoculation. a Nasal and (b) lung colonisation with Streptococcus pneumoniae assessed by routine culture methods. Differences between the groups were significant, 2-way ANOVA, (a, p=0.0003, b, p=0.003). Nose (c, e and g) and lung (d, f and i) microbiomes compared for OTU count (c and d), Diversity (e and f) and OTU2 abundance (g and h). Symbols for box and whisker plots as in Fig. 1. P values are for 2-way ANOVA between the wild type and Il17ra KO animal groups. ns = not significant