FIG 4.

RT-QuIC detection of amyloid formation in birthing fluids from clinically CWD-infected muntjac dams. For concentrated amniotic fluid from CWD-infected dams, values from preclinical specimens (4 dams) were not significantly different from control values, and values from clinical samples (2 dams) were significant at a P value of <0.0001. For allantoic fluid, values for both preclinical and clinical samples (2 dams each) from CWD-infected dams were not significantly different from values for negative dams (n = 2 dams). Number of replicates, 12 per dam per treatment group.