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. 2017 Jul 12;91(15):e00275-17. doi: 10.1128/JVI.00275-17

TABLE 1.

Experimental design and distribution of mice based on their human immune system reconstitution status and human tissue donor origin

Donor Group description Day of euthanasia Inoculum Avg reconstitution (%) (range)a
1 Reconstituted 3 Virus 30.2 (10.1–56.6)
1 Nonreconstituted 3 Virus NA
1 Nonreconstituted 3 Mock NA
2 Reconstituted 3 Virus 36.0 (16.1–68.7)
2 Reconstituted 3 Mock 44.3 (10.5–78.1)
2 Nonreconstituted 3 Virus NA
2 Nonreconstituted 3 Mock NA
1 Reconstituted 5 Virus 23.6 (11.2–40.7)
1 Reconstituted 5 Mock 24.4 (10.4–50.2)
1 Nonreconstituted 5 Virus NA
1 Nonreconstituted 5 Mock NA
2 Reconstituted 5 Virus 35.6 (23.0–50.3)
2 Reconstituted 5 Mock 32.6 (17.6–52.3)
2 Nonreconstituted 5 Virus NA
2 Nonreconstituted 5 Mock NA
a

Percentage of human versus mouse CD45+ cells, with sorting from 100 μl mouse peripheral blood. NA, nonapplicable.