FIG 4.

VLVs contain significant amounts of microRNA. (A) MicroRNA in VLVs. Total RNA was purified from VLVs and was then subjected to sizing and quantitation analysis using an Agilent 2100 Bioanalyzer. LM, Agilent lower marker (15 bp). (B) Percentages of microRNA reads from the host cell genome and the KSHV genome. (C) Pathway analysis of the top 24 human miRNAs (reads, >1,000) by the DIANA miRPath server (v3.0) (65). Shown are P values, corrected for the false discovery rate by the Benjamini-Hochberg procedure, for miRNAs associated with KEGG pathways.