TABLE 2.

Presence of cellular proteins in KSHV virions and VLVs^a

UniProtKB accession no.	Protein	Size (aa)	No. of peptides in:		Intensity ratio (VLV/virion)
			Virions	VLVs
P07355	Annexin A2	339	29	29	1.30
P60709	Beta-actin	376	23	30	1.65
Q09666	Neuroblast differentiation-associated protein	5,890	80	110	1.63
P14618	Pyruvate kinase isozymes M1/M2	605	35	42	2.49
P11142	Heat shock cognate 71-kDa protein	646	29	32	1.25
P04406	Glyceraldehyde-3-phosphate dehydrogenase	293	22	29	1.54
P08107	Heat shock 70-kDa protein 1A/1B	641	24	30	2.32
P06733	Alpha-enolase	341	22	30	1.73
P62937	Peptidyl-prolyl cis-trans isomerase A	165	14	17	1.39
P11021	78-kDa glucose-regulated protein	654	34	20	1.14
P08758	Annexin A5	320	23	22	0.86
P08195	4F2 cell surface antigen heavy chain	631	18	28	2.82
P08133	Annexin A6	673	25	30	1.26
P07237	Protein disulfide-isomerase	508	28	12	1.12
P21333	Filamin-A	2,647	29	58	3.77
P63104	14-3-3 protein zeta/delta	245	13	18	1.61
P62158	Calmodulin	149	10	13	1.56
P04075	Fructose-bisphosphate aldolase A	364	16	22	2.65
P60174	Triosephosphate isomerase	286	17	23	2.16
P23528	Cofilin-1	166	9	13	1.64
P08670	Vimentin	466	16	26	2.90
P68104	Elongation factor 1-alpha 1	462	10	17	2.29
P15311	Ezrin	586	16	24	2.10
P08238	Heat shock protein HSP 90-beta	724	10	19	3.09
P60903	Protein S100-A10	97	9	11	0.90
P05556	Integrin beta-1	798	18	22	1.46
P30101	Protein disulfide-isomerase A3	505	22	13	1.25
P04083	Annexin A1	346	21	20	1.15
P07900	Heat shock protein HSP 90-alpha	732	11	22	3.14
P37802	Transgelin-2	199	13	16	1.64

^aThe cellular proteins encoded by the top 30 genes are listed in order of decreasing signal intensity of the gene in VLVs.