Fig. S5.

Chronic intrathecal treatment with G-CSF-RAb does not alter disease recovery post colitis. Colitis was induced by adding 2.5% DSS in the drinking water of mice. On day 5, DSS mice were on water regimen for 5 wk. During the recovery period, mice were treated twice a week with either G-CSFR–blocking antibody (blue square; n = 11) or control IgG (red circle; n = 6). A control group that was not exposed to DSS received intrathecal PBS (n = 4). Recovery of colitis was monitored by weighing mice weekly (A) and macroscopic scoring of colonic tissue damages (B) as previously described (46).