Fig. S7.

Temperature compensation of central and peripheral oscillators in Per2::LucSV mice. (A) Average periods of central (SCN) and peripheral (adrenal, pituitary, lung, cornea, and liver) tissues are shown for both Per2::Luc and Per2::LucSV heterozygous mice within the range of temperatures tested (Per2::Luc data were adopted from ref. 43). All tissues show temperature compensation (Q10 value near 1.0). The periods of the Per2::LucSV oscillators are consistently longer (∼1 h) than those of Per2::Luc. Closed circle, Per2::Luc; open circle, Per2::LucSV. The y-error bars represent SE. (B) Comparison of Q10 values of five tissues from Per2::Luc and Per2::LucSV mice.