Fig. 1.

Overall structure of the Tte-MTase complex bound to DNA and SAM. (A) Schematics of the domain architectures of the S and M subunits of the type I R-M system from T. tengcongensis. The dashed lines indicate the disordered regions in the crystal structure. (B) Ribbon diagram of the structure of two Tte-MTase complexes in complex with one DNA and two SAM molecules in the asymmetric unit shown in two different views. Same color code as in A. The two MTase complexes are related by a noncrystallographic twofold symmetry. The individual domains of S and M subunits have been labeled in the Upper and Lower panels, respectively. The SAM molecules are shown in space-filling presentation and colored in green.