Table 2.
The statistics of non-synonymous somatic mutations in the pan-cancer driver (pcDriver) genes‡.
Cancer | White | Black | Asian | P-value | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q1 | Q2 | Q3 | Q1 | Q2 | Q3 | White::Black | White::Asian | Black::Asian | |
BLCA | 7 | 11 | 16 | 5 | 8 | 13 | 3.5 | 7 | 11 | 1.9E-01 | 5.0E-03 | 4.7E-01 |
GBM | 2 | 4 | 5 | 3 | 4 | 6 | 2 | 4 | 7 | 2.0E-01 | 7.2E-01 | 9.7E-01 |
HNSC | 4 | 7 | 11 | 4.75 | 8.5 | 11 | 3.5 | 6 | 13 | 5.6E-01 | 7.7E-01 | 7.2E-01 |
KIRC | 2 | 3 | 5 | 1.25 | 3.5 | 4 | 1 | 2 | 2 | 3.0E-01 | 1.5E-02 | 2.9E-01 |
LUAD | 5 | 9 | 15 | 10 | 13 | 18 | 5.75 | 9.5 | 18.25 | 6.8E-03 | 6.2E-01 | 4.6E-01 |
LUSC | 6 | 10 | 14 | 6 | 10 | 14 | 4 | 5 | 10 | 1.0E+00 | 1.4E-01 | 1.6E-01 |
BRCA | 1 | 3 | 4 | 1 | 3 | 4 | 2 | 3 | 5 | 7.9E-01 | 1.4E-01 | 1.4E-01 |
OV | 1 | 2 | 3 | 2 | 3 | 3 | 1 | 2.5 | 4.25 | 2.4E-01 | 5.8E-01 | 8.9E-01 |
UCEC | 5 | 8 | 15 | 4 | 5 | 12 | 5 | 7 | 60 | 2.4E-02 | 3.4E-01 | 1.7E-02 |
COAD | 5 | 7 | 12 | 5.5 | 7 | 15.5 | 5 | 10 | 73 | 9.3E-01 | 3.5E-01 | 4.7E-01 |
THCA | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 6.7E-01 | 6.3E-01 | 5.6E-01 |
CESC | 2 | 3 | 7 | 2 | 3.5 | 6.25 | 1 | 2 | 4.5 | 9.3E-01 | 8.1E-02 | 2.0E-01 |
ESCA | 3 | 5 | 7 | 6.25 | 6.5 | 6.75 | 3 | 5 | 6 | 2.7E-01 | 8.4E-01 | 2.0E-01 |
KIRP | 1 | 2 | 4 | 1 | 1 | 2.5 | 0.75 | 1.5 | 2.25 | 2.7E-02 | 5.0E-01 | 8.2E-01 |
LIHC | 2 | 3.5 | 5 | 3 | 4 | 6.5 | 2 | 3 | 6 | 2.0E-01 | 7.9E-01 | 3.2E-01 |
STAD | 3 | 6 | 10.5 | 4 | 19.5 | 36.25 | 2 | 4 | 11 | 3.0E-01 | 4.0E-01 | 2.2E-01 |
‡Q1, Q2 and Q3 are the first quantile, the second quantile (median) and the third quantile of mutation numbers, respectively. The number of tumor samples in each cancer-race group is the same as that in Table 1. P-values are calculated by the Mann Whitney test.