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. 2017 Oct 20;3:31. doi: 10.1038/s41531-017-0033-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Cell apoptosis in the SN of Nrf2 (+/+) and Nrf2 (−/−) mice after treatment with PQ, MPTP or saline (n = 3). a Each microgram (400×) shows a representative view of apoptosis in the SN of each group. b TUNEL-positive rate in each group. We counted the number of TUNEL staining positive cells and the number of total cells, and calculated the TUNEL staining positive rate (the number of TUNEL positive cells/total number of cells x 100%). ▲ Nrf2 (+/+) PQ10 vs. Nrf2 (+/+) saline (p < 0.01), ■Nrf2 (+/+) MPTP30 vs. Nrf2 (+/+) saline (p < 0.01), ◆Nrf2 (−/−) PQ10 vs. Nrf2 (−/−) saline (p < 0.01), ●Nrf2 (−/−) MPTP30 vs. Nrf2 (−/−) saline (p < 0.01)