Table 2.

The mRNA expression level of Sp3, a suggested target gene of miR-380-3p, in the substantia nigra of Nrf2 (+/+) and Nrf2 (−/−) mice after treatment with PQ, MPTP or saline (≥2 fold, p < 0.05)

Contrast	Fold change	p-value	Regulation
Nrf2 (+/+) PQ10 vs Nrf2 (−/−) PQ10	2.05	1.44 × 10−2	Up
Nrf2 (−/−) MPTP30 vs Nrf2 (−/−) PQ10	3.65	1.69 × 10−2	Up
Nrf2 (+/+) MPTP30 vs Nrf2 (+/+) PQ10	2.26	1.35 × 10−2	Up
Nrf2 (+/+) MPTP30 vs Nrf2 (+/+) Saline	2.61	4.44 × 10−2	Up