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. 2017 Oct 20;7:13670. doi: 10.1038/s41598-017-13722-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Associations between diversity, the hippurate trend, diet and OTUs and collapsed taxa with MetS status. (a) Shows the associations between MetS with Shannon diversity, the hippurate trend, and OTUs/taxa (significantly associated with hippurate, the diet score and MetS) represented as betas with SEs; all variables have been standardized. The diet score was not significantly associated with MetS. (b) Shows the percentage variance in the metabolite trend and MetS that was accounted for by the MetS association with Shannon diversity or associated OTUs/taxa. Abbreviations: MetS, metabolic syndrome; OTU, operational taxonomic unit; NA, not applicable.