Fig. 1.

Lack of Nfix improves signs of muscular dystrophy. a Hematoxylin and eosin (H&E) and Milligan’s trichrome staining of tibialis anterior (left) and diaphragm (right) muscles at 3 weeks of age; N = 12 Sgca null and 6 Sgca null:Nfix null mice. Scale bar 100 μm. b Hematoxylin and eosin (H&E) and Milligan’s trichrome staining of tibialis anterior (left) and diaphragm (right) muscles at 5 weeks of age; N = 5 Sgca null and 5 Sgca null:Nfix null mice. Scale bar 100 μm. See also Supplementary Fig. 1 for the analysis of central nucleation in tibialis anterior and diaphragm muscles at 3 and 5 weeks