Table 2.

Univariate analysis of risk factors for development of bladder tumour after surgical management of UTUC.

Variable	Development of bladder tumour, n/N (%)		P
	No	Yes
Gender
Male	138/262 (53)	124/262 (47)	0.6
Female	20/35 (57)	15/35 (43)
History of bladder tumour (preoperative)
No	134/248 (54)	114/248 (46)	0.5
Yes	24/49 (49)	25/49 (51)
Concomitant bladder tumour
No	111/219 (51)	108/219 (49)	0.4
Yes	47/78 (60)	31/78 (40)
Side of the tumour
Right	65/135 (48)	70/135 (52)	0.1
Left	93/162 (57)	69/162 (43)
Diagnostic ureteroscopy
Not done	90/173 (52)	83/173 (48)	0.6
Done	68/124 (55)	56/124 (45)
Surgical approach
Open RNU	141/260 (54)	119/260 (46)	0.6
Lap. RNU	9/24 (37)	15/24 (63)
Conservative	8/13 (62)	5/13 (38)
Site of the tumour
Kidney (pelvicalyceal)	74/121 (61)	47/121 (39)	0.07
Ureter	57/121 (47)	64/121 (53)
Kidney and ureter	27/55 (49)	28/55 (51)
Ureteric tumour
No	73/121 (60)	48/121 (40)	0.04
Yes	85/176 (48)	91/176 (52)
Site of the ureteric tumours
No	73/120 (61)	47/120 (39)	0.09
Multicentric	11/27 (41)	16/27 (59)
Lumbar	15/24 (63)	9/24 (37)
Iliac	7/18 (39)	11/18 (61)
Pelvic	52/108 (48)	56/108 (52)
Positive bladder cuff for TCC
No	148/280 (53)	132/280 (47)	0.6
Yes	10/17 (59)	7/17 (41)
Multifocality
No	105/193 (54)	88/193 (46)	0.5
Yes	53/104 (51)	51/104 (49)
Presence of CIS
No	148/282 (52)	134/282 (48)	0.2
Yes	10/15 (67)	5/15 (33)
Tumour grade
Grade I TCC	8/13 (62)	5/13 (38)	0.2
Grade II TCC	91/184 (49)	93/184 (51)
Grade III TCC	59/100 (59)	41/100 (41)
Tumour stage
Non muscle invasive	96/194 (49)	98/194 (51)	0.07
Muscle invasive.	62/103 (60)	41/103 (40)

Percentages were rounded to whole numbers.