Table 3.
Univariate analysis of risk factors for development of bladder tumour after surgical management of UTUC in patients after elimination of patients who had previous and/or concomitant bladder tumour.
| Variable | Development of bladder tumour, n/N (%) |
P | |
|---|---|---|---|
| No | Yes | ||
| Gender | |||
| Male | 88/168 (52) | 80/168 (48) | 0.9 |
| Female | 12/23 (52) | 11/23 (48) | |
| Side of the tumour | |||
| Right | 45/86 (52) | 41/86 (48) | 0.9 |
| Left | 55/105 (52) | 50/105 (48) | |
| Diagnostic ureteroscopy | |||
| Not done | 60/116 (52) | 56/116 (48) | 0.8 |
| Done | 40/75 (53) | 35/75 (47) | |
| Surgical approach | |||
| Open NU | 91/171 (53) | 80/171 (47) | 0.014 |
| Lap. NU | 4/15 (27) | 11/15 (73) | |
| Conservative | 5/5 (100) | – | |
| Site of the tumour | |||
| Kidney (pelvicalyceal) | 57/96 (59) | 39/96 (41) | 0.1 |
| Ureter | 32/67 (48) | 35/67 (52) | |
| Kidney and ureter | 11/28 (39) | 17/28 (61) | |
| Ureteric tumour | |||
| No | 57/97 (59) | 40/97 (41) | 0.06 |
| Yes | 43/94 (46) | 51/94 (54) | |
| Positive bladder cuff for TCC | |||
| No | 96/183 (52) | 87/183 (48) | 0.8 |
| Yes | 4/8 (50) | 4/8 (50) | |
| Multifocality | |||
| No | 66/120 (55) | 54/120 (45) | 0.3 |
| Yes | 34/71 (48) | 37/71 (52) | |
| Presence of CIS | |||
| No | 95/182 (52) | 87/182 (48) | 0.8 |
| Yes | 5/9 (56) | 4/9 (44) | |
| Tumour grade | |||
| Grade I TCC | 3/5 (60) | 2/5 (40) | 0.6 |
| Grade II TCC | 61/122 (50) | 61/122 (50) | |
| Grade III TCC | 36/64 (56) | 28/64 (44) | |
| Tumour stage | |||
| Non-muscle invasive | 64/127 (50) | 63/127 (50) | 0.4 |
| Muscle invasive | 36/64 (56) | 28/64 (44) | |
Percentages were rounded to whole numbers.