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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Nature. 2017 May 24;546(7656):107–112. doi: 10.1038/nature22342

Extended Data Figure 3. Fsh Antibody Markedly Reduces High-Fat Diet-Induced Obesity in 8-Month-Old Mice.

Extended Data Figure 3

Effect of Fsh antibody (Ab) or goat IgG (200 µg/day/mouse, i.p.) injected daily into 8-month-old C57BL/6 male mice (Charles Rovers) pair-fed on high-fat diet (n=2 or 3 mice/group) (HFD, see Methods). Shown are food intake and body weight (a); fat mass, fat mass/TM (FM/TM) and lean mass/TM (LM/TM) (b); and total (TFV), subcutaneous (SFV) and visceral (VFV) fat volume (coronal and transverse sections; visceral, red; subcutaneous, yellow) (c). Two-Tailed Student’s T-Test; *P≤0.05; ^P=0.06, mean ± SEM.