. Author manuscript; available in PMC: 2017 Oct 23.

Published in final edited form as: Oncogene. 2017 Mar 13;36(28):3957–3963. doi: 10.1038/onc.2017.48

Table 1.

The functions of FOXC1 in different cancer types

Cancer subtypes	Cellular functions	Clinical outcomes	References
Breast cancer	Proliferation, migration, invasion, EMT, metastasis.	Poor prognosis	^{23, 31, 32, 34, 35, 38, 41}
Hepatocellular carcinoma	Invasion, EMT, metastasis.	Poor prognosis	^{66, 69, 70}
Acute myeloid leukemia	Monocyte lineage differentiation block, clonogenic potential.	Unknown	⁷¹
Pancreatic ductal adenocarcinoma	Unknown	Poor prognosis	⁶⁷
Gastric cancer	Unknown	Poor prognosis	⁶⁸
Renal cell carcinoma	Unknown	Unknown	^{72, 73}
Cholangiocarcinoma	Unknown	Unknown	⁷⁴
Non-small cell lung cancer	Unknown	Poor prognosis	⁷⁵
Prostate cancer	Unknown	Unknown	^{76, 77}
Melanoma	Proliferation, migration, invasion.	Poor prognosis	⁷⁸
Endometrial cancer	Proliferation, migration, invasion.	Unknown	^{79, 80}