Table 2.
Depression and anxiety scores in the probiotic treatment (HN001) and placebo groups.
| Mean | Standard deviation | Univariable effect size (95%CI), p-value | Multivariable† effect size (95%CI), p-value | ||
|---|---|---|---|---|---|
| Depression scoresa | |||||
| HN001 | N = 194 | 7.7 | 5.4 | -1.2 (-2.4, -0.1) | -1.2 (-2.3, -0.1) |
| Placebo | N = 187 | 9.0 | 6.0 | p = 0.035 | p = 0.037 |
| Anxiety Scoresa | |||||
| HN001 | N = 192 | 12.0 | 4.0 | -1.1 (-1.9, -0.2) | -1.0 (-1.9, -0.2) |
| Placebo | N = 187 | 13.0 | 4.3 | p = 0.014 | p = 0.014 |
a
Three participants had incomplete anxiety data on the STAI6 and one had incomplete depression data on the EPDS, therefore scores could not be calculated.
†
Adjusted for infant colic and time since birth that questionnaires were completed.