Table 1.

Sequences and structures of CpG ODNs.

ODN	Kd (nM)	Nucleotide sequence (5′ to 3′)	Palindrome
ODN2395	9.8	t*c*g*t*c*g*t*t*t*t*c*g*g*c*g*c*g*c*g*c*c*g	+
ODN2395(5meC)	100	t*mc*g*t*mc*g*t*t*t*t*mc*g*g*mc*g*mc*g*mc*g*mc*mc*g	+
ODN2395(p)	58.1	tcgtcgttttcggcgcgcgccg	+
ODN2395mut(p)	59.2	tgctgcttttggggggcccccc	+
ODN1826(p)	N.D.	tccatgacgttcctgacgtt	−
ODN1826(s)	28	t*c*c*a*t*g*a*c*g*t*t*c*c*t*g*a*c*g*t*t	−
ODN1668(p)	1250	tccatgacgttcctgatgct	−
ODN1668(s)	83	t*c*c*a*t*g*a*c*g*t*t*c*c*t*g*a*t*g*c*t	−
ODN1585(p)	107	ggggtcaacgttgagggggg	+
ODN-D-SL03	125	t*c*g*c*g*a*a*c*g*t*t*c*g*c*c*g*c*g*t*t*c*g*a*a*c*g*c*g*g	+
ODN21798	80	t*cg*t*cg*t*cg*a*t*cg*g*c*g*cg*c*g*c*c*g	+
D35	77.5	g*gtgcatcgatgcagggg*g*g	+

N.D., not detectable.

*Phosphorothioate bond.

mc, 5′methyl-cytosine.