Table 4.
QST measures across clusters adjusted for race and study site.
| Cluster 1 Higher Function Minimal Movement- Evoked Pain (n=145) |
Cluster 2 Moderate Function Mild Movement- Evoked Pain (n=101) |
Cluster 3 Lower Function Severe Movement- Evoked Pain (n=24) |
Adjusted p-value |
|
|---|---|---|---|---|
| PPT- Medial Knee, mean ± SD | 293 ± 159 | 275 ± 161 | 191 ± 118 | 0.014 |
| PPT- Lateral Knee, mean ± SD | 312 ± 173 | 293 ± 164 | 208 ± 105 | 0.019 |
| PPT- Arm, mean ± SD | 247 ± 169 | 248 ± 170 | 152 ± 74 | 0.028 |
| PPT- Trapezius, mean ± SD | 275 ± 175 | 255 ± 172 | 189 ± 89 | 0.070 |
| PPT- Quadriceps, mean ± SD | 434 ± 229 | 405 ± 218 | 311 ± 142 | 0.043 |
| Punctate Pain, Hand, mean ± SD | 11.9 ± 16.7 | 11.0 ± 14.9 | 20.4 ± 24.2 | 0.044 |
| Punctate Pain, Knee, mean ± SD | 16.1 ± 19.8 | 13.9 ± 16.6 | 32.6 ± 28.5 | <0.0001 |
| CPT-16°C, mean ± SD seconds | 34.0 ± 19.3 | 33.7 ± 17.8 | 29.6 ± 16.1 | 0.587 |
| CPT-12°C, mean ± SD seconds | 54.8 ± 11.9 | 49.5 ± 15.9 | 49.0 ± 15.5 | 0.008 |
| CPT-8°C, mean ± SD seconds | 48.6 ± 16.7 | 41.6 ± 20.5 | 39.0 ± 19.3 | 0.004 |
| HPT- Arm, mean ± SD | 41.7 ± 3.3 | 41.7 ± 3.3 | 41.1 ± 3.5 | 0.710 |
| HPT- Knee, mean ± SD | 42.1 ± 3.1 | 41.7 ± 3.5 | 41.1 ± 3.9 | 0.334 |
| Heat TS- Knee, mean ± SD | 0.3 ± 14.0 | 0.6 ± 14.3 | 8.7 ± 20.1 | 0.045 |
| Punctate TS- Arm, mean ± SD | 13.3 ± 16.1 | 19.4 ± 22.6 | 24.1 ± 20.5 | 0.009 |
| Punctate TS- Knee, mean ± SD | 18.4 ± 18.0 | 23.6 ± 21.5 | 25.2 ± 18.0 | 0.084 |