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. Author manuscript; available in PMC: 2018 Oct 27.
Published in final edited form as: Vaccine. 2017 Sep 28;35(45):6137–6142. doi: 10.1016/j.vaccine.2017.09.054

Figure 2. Neutralizing antibody in infants vaccinated with IPR8-R848, IPR8-R848+flg or IPR8+m229.

Figure 2

Neutralizing antibody titers in plasma were measured over the course of vaccination by assessing inhibition of the ability of a GFP expressing PR8 virus to infect U937 cells. Neutralization titer was defined as the half maximal inhibitory concentration (IC50), i.e. the dilution factor at which 50% infectivity was blocked. Individual animals and geometric means are shown. Significance over the time course was assessed by one-way ANOVA (significance indicated on the legend). *p<0.05