Table 2.

Univariate and multivariate regression analysis for mortality risk in the multi-site (derivation) cohort. OR: Odds Ratio; CI: confidence interval.

Variable	Univariate			Multivariate (N = 1209)
	OR	CI 95%	p	OR	CI 95%	p
Cardiac disease	2.10	1.30–3.39	0.002	–	–	–
Neurological disease	2.60	1.55–4.36	< 0.001	–	–	–
Chronic renal failure	3.41	1.92–6.06	< 0.001	2.46	1.17–5.18	0.017
CURB-65 ≥ 3	6.35	3.89–10.37	< 0.001	4.13	2.23–7.65	< 0.001
Initial ICU admission	3.39	1.88–6.09	< 0.001	2.26	1.04–4.90	0.039
Apropriate antibiotic treatment	0.27	0.15–0.48	< 0.001	0.26	0.14–0.49	< 0.001
Lymphocytes (cell/mm3) (Ln)	0.57	0.42–0.78	< 0.001	0.66	0.44–0.98	0.044