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. 2017 Aug 28;14(5):5179–5188. doi: 10.3892/ol.2017.6851

Table IV.

Clinicopathological characteristics of patients with brain tumors and D-Loop mutation status.

D-loop status, n (%)

Parameter Total patients, no. (%) Mutation No mutation P-value
No. of patients 49 (100) 25 (51.0) 24 (49.0)
Sex
  Male 29 (59.2) 15 (51.7) 14 (48.3) 1.000
  Female 20 (40.8) 10 (50.0) 10 (50.0)
Age, years
  <45 20 (40.8)   7 (35.0) 13 (65.0) 0.0845
  ≥45 29 (59.2) 18 (62.1) 11 (37.9)
Ethnicity
  Malaysian 42 (85.7) 22 (52.4) 20 (47.6) 0.8716
  Chinese   5 (10.2)   2 (40.0)   3 (60.0)
  Indian   2 (4.1)   1 (50.0)   1 (50.0)
Histological tumor types (grade)
  Pilocytic astrocytoma (I)   6 (12.2)   2 (33.3)   4 (66.7) 0.1282
  Astrocytomas (II) 2 (4.1) 0 (0) 2 (100)
  Anaplastic astrocytomas (III)   5 (10.2)   2 (40.0)   3 (60.0)
  Glioblastomas multiform (IV) 16 (32.7) 12 (75.0)   4 (25.0)
  Ependymoma 2 (4.1)   1 (50.0)   1 (50.0)
  Oligodendroglioma 3 (6.1) 0 (0) 3 (100)
  Meningioma (I) 15 (30.6)   8 (53.3)   7 (46.7)