Table III.
Comparison of clinical and demographic features between patient groups stratified by tCAIX (<75th vs. ≥75th percentiles).
| Low tCAIX (n=126) | High tCAIX (n=42) | ||||
|---|---|---|---|---|---|
| Patient characteristics | n | % | n | % | χ2 P-value |
| Sex | 0.929 | ||||
| Male | 70 | 55.6 | 23 | 54.8 | |
| Female | 56 | 44.4 | 19 | 45.2 | |
| Age | |||||
| Years (mean, SD) | 60.8 (14.4) | 58.5 (13.0) | |||
| History of tobacco smoking | 0.115 | ||||
| Never | 32 | 25.4 | 16 | 38.1 | |
| Ever | 94 | 74.6 | 26 | 61.9 | |
| History of alcohol consumption | 0.144 | ||||
| Never | 13 | 10.3 | 8 | 19.1 | |
| Ever | 112 | 88.9 | 34 | 80.9 | |
| Missing | 1 | 0.8 | |||
| pT status | 0.019a | ||||
| pT1/pT2 (low) | 80 | 63.5 | 18 | 42.9 | |
| pT3/pT4 (high) | 46 | 36.5 | 24 | 57.1 | |
| Missing | 0 | 0.0 | 0 | 0.0 | |
| pN status | 0.004a | ||||
| N0 neck | 74 | 58.7 | 14 | 33.3 | |
| N+ neck | 52 | 41.3 | 28 | 66.7 | |
| Tumor differentiation | 0.170 | ||||
| Well | 30 | 23.8 | 5 | 11.9 | |
| Moderate | 64 | 50.8 | 26 | 61.9 | |
| Poor | 23 | 18.3 | 11 | 26.2 | |
| Missing | 9 | 7.1 | 0 | 0.0 | |
| Oral cavity subsite | 0.068 | ||||
| Oral tongue | 46 | 36.5 | 17 | 40.5 | |
| Floor of mouth | 25 | 19.8 | 14 | 33.3 | |
| Buccal | 9 | 7.1 | 5 | 11.9 | |
| Gingiva | 32 | 25.4 | 5 | 11.9 | |
| Others/site NOS | 14 | 11.1 | 1 | 2.4 | |
| Treatment | 0.032a | ||||
| Surgery alone | 58 | 46.0 | 11 | 26.2 | |
| Surgery + RT | 31 | 24.6 | 9 | 21.4 | |
| Surgery + chemo + RT | 32 | 25.4 | 20 | 47.6 | |
| Surgery + chemo | 1 | 0.8 | 1 | 2.4 | |
| Incomplete data | 4 | 3.2 | 1 | 2.4 | |
a
P<0.05. OSCC, oral squamous cell carcinoma; CAIX, carbonic anhydrase IX; s, stromal; t, tumoral; CI, confidence interval; DSS, disease-specific survival; RT, radiotherapy; NOS, not otherwise specified.