Table 1.
Comparison of baseline characteristics and risk factors (safety set)
| Baseline characteristics | N (Cere/ Pla) | Cerebrolysin | Placebo | p-value | |
|---|---|---|---|---|---|
| Sex - Male (N, %) | 50/50 | 27 (54%) | 26 (52%) | ns | |
| Age (Mean, SD) | 49/49 | 69.0 (10.7) | 66.5 (12.2) | ns | |
| NIHSS Score (Mean, SD) | 49/50 | 11.1 (5.0) | 9.1 (4.8) | 0.02a | |
| mRS Score (Mean, SD) | 47/49 | 3.9 (1.0) | 3.4 (1.1) | 0.05b | |
| Prevalence of risk factors | N (Cere/ Pla) | Cerebrolysin | Placebo | OR | p-valuec |
| Previous Stroke | 50/50 | 28% | 18% | 1.8 | ns |
| Weakness | 50/50 | 24% | 22% | 1.1 | ns |
| Aphasia | 50/50 | 28% | 10% | 2.8 | 0.04 |
| Cardiac Disease | 50/50 | 28% | 36% | 0.8 | ns |
| Past/ Current Smoker | 50/50 | 22% | 28% | 0.8 | ns |
| Hypertension | 50/50 | 78% | 82% | 1.0 | ns |
| Obesity | 50/50 | 28% | 56% | 0.5 | 0.01 |
| Increased Serum Lipids | 50/50 | 56% | 62% | 0.9 | ns |
| Diabetes | 50/50 | 38% | 34% | 1.1 | ns |
| Family History of Stroke | 50/50 | 20% | 8% | 2.5 | ns |
| Cere = Cerebrolysin; NIHSS = National Institutes of Health Stroke Scale; mRS = modified Rankin Scale; ns = not significant; OR = odds ratio; Pla = placebo; SD = standard deviation. aWilcoxon-Mann-Whitney test (MW=0.36); bWilcoxon-Mann-Whitney test (MW=0.39); cFisher’s exact test; data as available. |