Table 3.

Brain regions exhibiting altered neural reactivity as a function of overt (n = 24) or covert (n = 22) SSRI administration.

Contrast	MNI coordinate			Cluster sizea	Z value	p value
Brain region	x	y	z
Overt > covert SSRI
R posterior cingulate gyrus (BA23)	9	− 28	28	3780	4.58	< 0.0001
L mid temporal gyrus (BA39)	− 30	− 58	25	513	3.93	< 0.0001
L posterior cingulate gyrus (BA31)	− 21	− 28	34	351	3.83	< 0.0001
L inferior frontal gyrus (BA46)	− 36	35	1	270	3.69	0.0001
Covert > overt SSRI
ns

Whole brain search, p ≤ 0.001 k > 10; SSRI = selective serotonin reuptake inhibitor (escitalopram); R = right, L = left; BA = Brodmann area.

^aVolume in mm³, voxel size: 27 mm³.