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Duration of hIL-1RA in the hippocampus after a single ICM injection. hIL-1RA protein was assayed in the hippocampus 2 h, 1 d, 2 d, 4 d and 14 d post-ICM treatment with hIL-1RA (100 μg). Means with different letter designations (a, b, c, or d) are significantly different (p<.05) from each other. Data are presented as the mean±SEM.
