Table 2.

Matrix Effect (ME) at Eight Calibration Points Using Aqueous (Matrix-Free) Solutions and RBCs from Bovine (Bovine)

	pmol	mean peak area				area ratio		ratioa	ME%	IS	IS-compensated ME
		analyte		IS		matrix free	bovine		analyte
		matrix free	bovine	matrix free	bovine
Cal A	8.29	63 105	31 836	259 384	137 543	0.24	0.23	0.24	50.4	53.0	1.0
Cal B	10.91	89 904	38 023	262 692	110 915	0.34	0.34	0.34	42.3	42.2	1.0
Cal C	16.58	132 366	58 094	268 016	117 422	0.49	0.49	0.49	43.9	43.8	1.0
Cal D	21.83	191 236	77 117	272 020	119 664	0.70	0.64	0.67	40.3	44.0	0.9
Cal E	33.16	281 336	118 103	266 962	119 057	1.05	0.99	1.02	42.0	44.6	0.9
Cal F	43.66	389 684	168 554	274 876	120 404	1.42	1.40	1.41	43.3	43.8	1.0
Cal G	66.32	566 098	254 415	266 594	123 205	2.12	2.06	2.09	44.9	46.2	1.0
Cal H	87.32	787 933	380 060	269 786	135 215	2.92	2.81	2.88	48.2	50.4	1.0
									7.6b	8.2b	4.7b

^aAverage ratio of matrix free analyte/IS and analyte/IS in bovine.

^bCoefficient of variation (%CV).