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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Lancet Child Adolesc Health. 2017 Sep 26;1(3):240–248. doi: 10.1016/S2352-4642(17)30044-5

Figure 3. Interplay between fat derived hormones and cytokines.

Figure 3

The excess of visceral adipose tissue is linked to ectopic fat deposition and abnormal adipokines secretion. Obese patients with higher visceral adiposity show lower adiponectin and relatively low leptin levels despite similar body mass index and body fat percentage. Lower Adiponectin is associated with higher ectopic fat deposition in skeletal muscle and liver. Lower Leptin is associated with lower insulin sensitivity.