Table 6. Number of samples for which IHC and gene expression yield receptor positive/unknown/negative.
| gene expression | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ER | PGR | HER2 | |||||||
| GE – | GE 0 | GE + | GE – | GE 0 | GE + | GE – | GE 0 | GE + | |
| IHC – | 887 | 100 | 86 | 590 | 357 | 142 | 1560 | 20 | 7 |
| IHC 0 | 273 | 81 | 257 | 365 | 282 | 473 | 593 | 88 | 74 |
| IHC + | 70 | 157 | 969 | 75 | 143 | 453 | 271 | 119 | 148 |
| Critical GE | 338 | 782 | 227 | ||||||
| Rate of discordant samples | 5% | 8% | 10% | ||||||
| Rate of conclusive samples | 92% | 79% | 87% | ||||||
IHC 0: no IHC measurement available.
GE 0: expression value within the critical domain, and no decision can be made. Boundaries of critical domains were computed by the ExMax-method.
Bold print: discordant samples.
Note that results shown in this table are obtained step by step via the methods explained in ‘Material and Methods’.