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. 2017 Aug 24;8(44):77341–77359. doi: 10.18632/oncotarget.20474

Table 6. Number of samples for which IHC and gene expression yield receptor positive/unknown/negative.

gene expression
ER PGR HER2
GE – GE 0 GE + GE – GE 0 GE + GE – GE 0 GE +
IHC – 887 100 86 590 357 142 1560 20 7
IHC 0 273 81 257 365 282 473 593 88 74
IHC + 70 157 969 75 143 453 271 119 148
Critical GE 338 782 227
Rate of discordant samples 5% 8% 10%
Rate of conclusive samples 92% 79% 87%

IHC 0: no IHC measurement available.

GE 0: expression value within the critical domain, and no decision can be made. Boundaries of critical domains were computed by the ExMax-method.

Bold print: discordant samples.

Note that results shown in this table are obtained step by step via the methods explained in ‘Material and Methods’.