Table 1.
Clinical feature | Number of patients | |
---|---|---|
Age, yr (N = 17) | Median: 8 yr; range: 1–15 yr | |
Sex (N = 17) | Male: n = 11 | Female: n = 6 |
Prodrome (N = 16) | Abdominal pain | n = 9b |
Vomiting | n = 9b | |
Diarrhea | n = 8b | |
Fever | n = 4 | |
Other | a | |
Clinical features (N = 16) | Hematuria | n = 12 |
Proteinuria | n = 13 | |
Oligoanuria | n = 10 | |
Hypertension | n = 9 | |
Edema | n = 3 | |
Triggering event (N = 17) | Infection | n = 7 |
None identified | n = 10 | |
Extrarenal manifestations (N = 16) | None | n = 8 |
Seizures | n = 3 | |
Hepatitis | n = 2 | |
Epistaxis | n = 2 | |
Pancreatitis | n = 1 | |
Altered consciousness | n = 1 |
Laboratory features at presentation | Mean (range) |
---|---|
Hemoglobin, g/dl (N = 17) | 6.6 (4–9.1) |
Platelet count, ×109 (N = 17) | 52 (9–134) |
Creatinine, μmol/l (N = 17) | 331 (61–1131) |
Lactate dehydrogenase, U/L (N = 16) | 4460 (887–17,584) |
Antinuclear antibodies (N = 12) | 1/12 positive 1:40 |
Other prodromal symptoms reported in ≤2 patients: headache, malaise, cough, visible hematuria, petechiae, and flulike illness.
Twelve patients had at least 1 gastrointestinal symptom (abdominal pain, vomiting, diarrhea).