Table 1.

Active RCTs on HOPE in OLT on clinicaltrials.gov (search date: 26 August 2017)

Trial number	Study centre	Study type	Enrolment	Donor group	Primary endpoint	Comment
NCT03124641 (present trial)	RWTH Aachen University, Aachen, Germany	RCT	46	ECD-DBD	Early graft function (peak ALT level)	Recruiting
NCT01317342	University of Zurich, Zurich, Switzerland	RCT	170*	DBD (ECD subgroup analysis only)	Major postoperative complications (Clavien grade≥III) and CCI*	Recruiting
NCT02584283	University of Groningen, Groningen, Netherlands	RCT	156	DCD (Maastricht category III)	Incidence of symptomatic NAS	Recruiting

*Information based on personal communication.

ALT, alanine aminotransferase; CCI, comprehensive complication index; DBD, donation of the brain death; DCD, donation of the cardiac death; ECD, extended criteria donation; HOPE, hypothermic oxygenated machine perfusion; NAS, non-anastomotic biliary strictures; OLT, orthotopic liver transplantation; RCT, randomised controlled trial; RWTH, Rheinisch-Westfälische Technische Hochschule.