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. 2016 Jun 23;8(44):75808–75821. doi: 10.18632/oncotarget.10257

Figure 6. Physiologic study to test the diuretic response of albumin-overloaded WT mice to the NKCC2 inhibitor furosemide (F).

Figure 6

A–D. WT mice were treated with either saline or albumin for up to 12 days and their diuretic response to vehicle V. or furosemide measured over 6 hr. Albumin overload reduced the urine volume (A) and urinary excretion of sodium (B), chloride (C), and potassium (D) in response to furosemide treatment. The values represent the means±SDs; n=6 in each group. *p<0.01 vs. vehicle-treated control mice. # p<0.01 vs. furosemide-treated control mice.