Table 1. Differential miRNA expression in exosomes between differentresponse to chemotherapy in osteosarcoma.

Good Responders vs. Control			Poor Responders vs. Contro
miR-Name	fold change	Adjusted p-value	miR-Name	fold change	Adjusted p-value
miR-21	0.824	0.0516	miR-21	11.392	0.0001
miR-27a	0.914	0.1021	miR-27a	6.774	0.0104
miR-148a	1.257	0.1875	miR-148a	5.540	0.0084
miR-135b	1.181	0.0533	miR-135b	4.347	0.0003
miR-9	1.125	0.2152	miR-9	2.676	0.0325
miR-214	1.165	0.0567	miR-214	2.621	0.0063
miR-210	0.959	0.0797	miR-210	2.428	0.0005
miR-300	2.028	0.0730	miR-300	2.173	0.0035
miR-665	1.705	0.0534	miR-665	1.778	0.0034
miR-145	2.329	0.0880	miR-145	1.729	0.0059
miR-543	0.940	0.2766	miR-543	1.516	0.0033
miR-382	0.946	0.0663	miR-382	1.424	0.0038
miR-183	1.257	0.2041	miR-183	0.829	0.0030
miR-133b	1.014	0.0640	miR-133b	0.774	0.0124
miR-34a	0.914	0.2928	miR-34a	0.768	0.0144
miR-490-3p	1.079	0.2925	miR-490-3p	0.753	0.0089
miR-646	0.646	0.2652	miR-646	0.747	0.0026
miR-146a	0.737	0.0609	miR-146a	0.722	0.0046
miR-144	0.763	0.2197	miR-144	0.678	0.0063
miR-217	1.035	0.0672	miR-217	0.669	0.0121
miR-489-3p	0.953	0.0601	miR-489-3p	0.655	0.0002
miR-100	1.173	0.2096	miR-100	0.616	0.0079
miR-95-3p	0.511	0.0630	miR-95-3p	0.616	0.0251
miR-143	0.678	0.1996	miR-143	0.486	0.0003
miR-195	1.035	0.0645	miR-195	0.467	0.0138
miR-206	1.853	0.0547	miR-206	0.435	0.0103
miR-133a	1.021	0.0810	miR-133a	0.423	0.0120
miR-124	1.094	0.0706	miR-124	0.403	0.0233
miR-199a-3p	1.035	0.2628	miR-199a-3p	0.240	0.0130
miR-382	1.569	0.1396	miR-382	0.028	0.0123