Table 2. Logistic regression analysis of exome array with biochemical recurrence after radical prostatectomy.
| SNPID | Chr | Alleles | Gene | Minor Allele Frequency | OR (95% CI) | p-value | |
|---|---|---|---|---|---|---|---|
| No BCR | BCR | ||||||
| rs4965121 | 15 | G > C | . | 0.05824 | 0.1152 | 2.106 (1.455–3.047) | 5.75E-05 |
| rs1128966 | 17 | C > G | NT5C3B | 0.1871 | 0.1083 | 0.5278 (0.379–0.735) | 0.000127 |
| rs1046404 | 17 | C > G | NT5C3B | 0.1871 | 0.1083 | 0.5278 (0.379–0.735) | 0.000127 |
| rs1046403 | 17 | A > G | NT5C3B | 0.1871 | 0.1088 | 0.5306 (0.381–0.7388) | 0.000145 |
| rs781831 | 17 | T > C | ZZEF1 | 0.3565 | 0.2593 | 0.6317 (0.4963–0.804) | 0.000176 |
| rs7009549 | 8 | A > G | . | 0.5121 | 0.4124 | 0.6689 (0.5379–0.8316) | 0.000283 |
| rs12871532 | 13 | C > T | . | 0.3663 | 0.2742 | 0.6536 (0.5156–0.8285) | 0.000417 |
| rs16964211 | 15 | G > A | CYP19A1 | 0.2952 | 0.2097 | 0.6335 (0.4895–0.82) | 0.000489 |
| rs3133745 | 8 | C > T | C8orf37-AS1 | 0.2401 | 0.1613 | 0.6088 (0.4585–0.8083) | 0.000551 |
| rs2071286 | 6 | G > A | NOTCH4 | 0.1693 | 0.1019 | 0.5565 (0.3955–0.7831) | 0.000672 |
| rs10853489 | 18 | A > G | . | 0.4041 | 0.4954 | 1.448 (1.166–1.797) | 7.73E-04 |
| rs7439186 | 4 | C > T | AMBN | 0.1349 | 0.2005 | 1.607 (1.214–2.127) | 0.000842 |
| rs2144425 | 6 | A > G | OR12D3, OR5V1 | 0.3113 | 0.2281 | 0.6539 (0.5087–0.8406) | 0.000866 |
| rs3935295 | 1 | G > A | PTPN7 | 0.1607 | 0.09677 | 0.5594 (0.3948–0.7927) | 0.000959 |
| rs4745571 | 9 | T > C | PRUNE2 | 0.1712 | 0.2419 | 1.545 (1.192–2.004) | 0.000966 |
| rs17168761 | 7 | T > C | AGMO | 0.3623 | 0.2765 | 0.6726 (0.5307–0.8523) | 0.000987 |
Abbreviations: SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval; BCR: biochemical recurrence.