Table 3. Multivariate Cox proportional models of potential predictors for biochemical recurrence of prostate cancer among men who underwent radical prostatectomy and accuracy analysis of established models according to presence of SNP informations.

	Clinical model			Clinico-genetic model
Variables	HR	95% CI	P value	HR	95% CI	P value
Age (yrs)	0.990	0.968–1.012	0.375	0.990	0.968–1.013	0.400
Initial PSA (ng/ml)	1.003	0.999–1.008	0.117	0.999	0.995–1.003	0.649
Pathologic Gleason score	2.428	1.742–3.385	< 0.001	2.600	1.878–3.600	< 0.001
Extracapsular extensioin	3.090	2.125–4.493	< 0.001	2.847	1.956–4.144	< 0.001
Seminal vesicle invasion	2.637	1.869–3.720	< 0.001	2.461	1.745–3.471	< 0.001
Positive surgical margin	1.972	1.438–2.706	< 0.001	2.010	1.463–2.762	< 0.001
Genetic risk score				1.630	1.454–1.826	< 0.001
Areas under curve of each multivariate models	0.844			0.880

Abbreviations: OR: odds ratio; CI: confidence interval; PSA: prostate specific antigen; SNP: single nucleotide polymorphism.