Figure 4. Comparison for the killing abilities of four hexon-chimeric oncolytic adenovirus (P9, P9-4C, GP and Ad) in gastric CAFs, GPFs and BJ dependently on a series of MOI (0-500).

The three fiber-modified hexon-chimeric oncolytic adenovirus (P9, P9-4C and GP) effectively inhibited the viability of gastric CAFs cells than GPFs and BJ cells at MOI = 1 initially and at MOI = 10 markedly, and without obviously effect on BJ cells at less than or equal to MOI = 10.