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(A) Recombinant overlapping peptides derived from native OVA were linked by LRMK, the target sequence of cathepsin S. SIINFEKL is the epitope presented on mouse H-2b. (B) Comparison of SIINFEKL presentation on dendritic cells after incubation of DC2.4 cells with 50 μg/ml native OVA or ROP-OVA for 13 hours. The experiment was repeated twice.
