Figure 6. 5-Aza restored perinatal nicotine-induced repression of PKCε in the LV tissues of male offspring.
Pregnant rats were treated with saline (control) or nicotine, and pups were administered with 5-Aza (i.p. 1mg/kg/day) on postnatal day 3, 7 and 10 after delivered. At one month of age, the protein abundance of PKCε in the absence (A) and in the presence (B) of 5-Aza treatment was determined in the left ventricle tissues isolated from male offspring. Data are means ± SEM (n = 4 animals/group from different litter). * P < 0.05 vs control.