Table 6. Associations of the TCF7L2 rs290481 T>C genetic variants with biochemistry characteristics in healthy controls.
| Genotype | Controls (n=782) | FPG (mmol/L) | P | Total cholesterol (mmol/L) | P | Triglyceride (mmol/L) | P | HDL-C (mmol/L) | P | LDL-C (mmol/L) | P | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | |||||||||||
| TT | 313 | 40.23 | 5.11±0.49 | 1.0 | 4.86±1.13 | 1.0 | 1.60±1.06 | 1.0 | 1.27±0.36 | 1.0 | 3.13±0.91 | 1.0 |
| TC | 341 | 43.83 | 5.13±0.50 | 0.627 | 4.88±0.95 | 0.794 | 1.53±0.85 | 0.349 | 1.32±0.38 | 0.064 | 3.13±0.74 | 0.966 |
| CC | 124 | 15.94 | 5.22±0.43 | 0.029 | 4.96±0.93 | 0.359 | 1.50±0.98 | 0.341 | 1.34±0.36 | 0.062 | 3.19±0.80 | 0.477 |
| TC+CC | 465 | 59.77 | 5.15±0.48 | 0.224 | 4.90±0.95 | 0.560 | 1.52±0.89 | 0.258 | 1.33±0.37 | 0.030 | 3.15±0.76 | 0.743 |
FPG: fasting plasma glucose;
HDL-C, high-density lipoprotein cholesterol;
LDL-C, low-density lipoprotein cholesterol;
Bold values are statistically significant (P <0.05)