Table 1. Baseline characteristics of stroke patients with AR and AS.
| Patients with AR | Patients with AS | Pa | |
|---|---|---|---|
| N (%) | 50(22.3) | 174(77.7) | <0.001 |
| Age, years medians (IQRs) | 65(57-77) | 63(56-74) | 0.632 |
| Sex, male/female, n | 29/21 | 94/80 | 0.618 |
| BMI, kg/m2 medians (IQRs) | 26.8(25.2-28.1) | 26.7(25.4-28.2) | 0.402 |
| SBP, mmHg medians (IQRs) | 142(120-155) | 136(115-150) | 0.198 |
| Vascular risk factors, n (%) | |||
| Hypertension | 36(72.0) | 118(67.8) | 0.574 |
| Diabetes | 22(44.0) | 60(34.5) | 0.218 |
| Coronary heart disease | 11(22.0) | 32(18.4) | 0.631 |
| Hypercholesterolemia | 19(38.0) | 61(35.1) | 0.775 |
| History of TIA | 15(30.0) | 34(19.5) | 0.115 |
| Smoking habit | 17(34.0) | 59(33.9) | 0.942 |
| Pre-stroke treatment, n (%) | |||
| Antihypertensive drug | 32(64.0) | 84(48.3) | 0.001 |
| Statin use | 15(30.0) | 62(35.6) | 0.336 |
| Administration of IV-tPA, n (%) | 10(20.0) | 32(18.4) | 0.803 |
| Median onset to ARU, (hr, IQR) | 20.2(14.3-24.2) | 17.5(13.2-22.8) | 0.205 |
| Median onset to DWI, (hr, IQR) | 15.4(11.0-16.8) | 13.2(9.5-14.7) | 0.368 |
| Stroke etiology no. (%) | 0.713 | ||
| Cardioembolic | 9(18.0) | 32(18.4) | |
| Small-vessel disease | 11(22.0) | 43(24.7) | |
| Large-vessel atherosclerosis | 17(34.0) | 66(37.9) | |
| Other | 7(14.0) | 17(9.8) | |
| Unknown | 6(12.0) | 16(9.2) | |
| Stroke syndrome no. (%) | 0.016 | ||
| Embolic strokes (TACS, PACS, and POCS) | 31(62.0) | 137(78.8) | |
| Arteriosclerotic strokes(LACS) | 19(38.0) | 37(21.2) | |
| NIHSS at admission, medians (IQR) | 8(5-15) | 3(1-6) | <0.001 |
| Lesion volumes, median(ml, IQR) | 13.21(8.51-23.88) | 4.26(1.74-11.62) | <0.001 |
| Laboratory data, median (IQR) | |||
| ARU | 585(566-613) | 450(410-477) | <0.001 |
| WBC, x109/L | 8.8(7.2-9.8) | 7.6(6.5-9.0) | 0.021 |
| Platelet, X103/ml | 245(210-273) | 238(206-270) | 0.556 |
| FBG, mmol/l | 5.77(4.89-6.90) | 5.21(4.55-6.42) | 0.032 |
| CRP, mg/l | 5.68(3.99-8.65) | 3.22(2.04-5.11) | 0.003 |
| Total cholesterol, mg/dl | 199(134-255) | 190(130-247) | 0.572 |
| LDL cholesterol, mg/dl | 128(101-145) | 125(98-140) | 0.637 |
ap value was assessed using Mann-Whitney U test or Chi-Square test.
AR, aspirin-resistant; AS, aspirin-sensitive; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; TPA-T: Tissue plasminogen activator-treated; CRP, C-reactive protein; FBG, fasting blood glucose; SBP, Systolic blood pressure; LACS, lacunar syndrome; PACS, partial anterior circulation syndrome; POCS, posterior circulation syndrome; TACS, total anterior circulation syndrome; BMI, body mass index; ARU, aspirin reaction units; DWI, Diffusion-Weighted Magnetic Resonance Imaging