Table 3. Relationship between ARU quartile and DWI infarct volume based on multivariate quartile regression analysis.
ARU at admission | Median Infarct Volume(ml, IQR)a | Multivariate Change in Infarct Volume (95% CI),mLa, b | P value c |
---|---|---|---|
Q1(<426) | 2.79(0.98-7.45) | Reference(1.00) | — |
Q2(426-465) | 4.03(1.72-9.37) | 1.15(0.95-2.53) | 0.105 |
Q3(466-532) | 4.92(2.12-12.99) | 1.92(1.31-3.16) | 0.021 |
Q4(>532) | 13.12(6.82-25.12) | 5.44(3.05-10.21) | <0.001 |
a P<0.001 for trend across quartiles
b adjusted for age, sex, BMI, stroke subtype, stroke syndrome, vascular risk factors, prior or acute treatment, Time from onset to ARU, time to MR imaging, NIHSS score and blood levels of WBC, Platelet, Total cholesterol, LDL cholesterol, CRP and FBG.
c Post hoc test of difference in DWI infarct volumes compared with reference Q1.
DWI, Diffusion-Weighted Magnetic Resonance Imaging; CRP, high C-reactive protein; FBG, fasting blood glucose; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; ARU, aspirin reaction units