Table 2. Characteristics for patients with benign vs. early-stage ovarian cancer (n=53).
| Characteristic | Benign (n=43) | Cancer, stage I and II (n=10) | P |
|---|---|---|---|
| Age (yr), median (range) | 45 (21-74) | 52.5 (24-73) | 0.910 |
| ≤46 | 25 (58.1) | 5 (50.0) | 0.730 |
| >46 | 18 (41.9) | 5 (50.0) | |
| Preoperative serum CA-125 (U/ml) | 176.7±429.3 | 652.3±1199.3 | 0.246 |
| ≤35 | 17 (39.5) | 3 (30.0) | 0.725 |
| >35 | 26 (60.5) | 7 (70.0) | |
| Preoperative ROMA (%) | 10.8±17.4 | 43.1±40.0 | 0.032 |
| Within normal range | 27 (64.3) | 3 (30.0) | 0.075 |
| Abnormal† | 15 (35.7) | 7 (70.0) | |
| Preoperative RMI | 642.7±1807.5 | 4860.7±10919.9 | 0.254 |
| ≤200 | 27 (64.3) | 5 (50.0) | 0.480 |
| >200 | 15 (35.7) | 5 (50.0) | |
| Preoperative CT or MRI | 0.001 | ||
| Benign | 23 (53.5) | 1 (10.0) | |
| r/o borderline malignancy | 9 (20.9) | 0 | |
| r/o cancer | 11 (25.6) | 9 (90.0) | |
| Laparoscopic operation | 0.031 | ||
| No | 21 (48.8) | 9 (90.0) | |
| Yes | 22 (51.2) | 1 (10.0) | |
| Tumor size (cm) | 8.4±5.1 | 13.1±5.6 | 0.013 |
| ≤10 | 33 (78.6) | 2 (20.0) | 0.001 |
| >10 | 9 (21.4) | 8 (80.0) | |
| Ascitesǂ | 0.114 | ||
| Absence | 39 (90.7) | 7 (70.0) | |
| Presence | 4 (9.3) | 3 (30.0) |
Values are presented as number (%) or mean±standard deviation.
*International Federation of Gynecology and Obstetrics (FIGO) stage I and II.
†Abnormal ROMA criteria: ≥7.4% (premenopause) and ≥25.3% (postmenopause).
ǂModerate to severe ascites on preoperative CT or MRI.
CT, computed tomography; MRI, magnetic resonance imaging; RMI, risk of malignancy index; ROMA, risk of ovarian malignancy algorithm; r/o rule out.