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. 2017 Aug 24;8(44):77317–77329. doi: 10.18632/oncotarget.20469

Table 1. Binding free energies (ΔGbind) and binding free energy differences (ΔΔGbind) for the Hsp27 WT, N1, N2 and C2 truncated mutants in complex with eIF4E. (ΔΔGbind=ΔGbind(WT)- ΔGbind(truncated)).

Complex ΔGbind(kcal/mol) ΔΔGbind(kcal/mol)
Hsp27 WT -11.86 ± 0.24 -
Hsp27 N1 -3.06 ± 0.27 -8.80
Hsp27 N2 -6.05 ± 0.23 -5.81
Hsp27 C1 -9.99 ± 0.25 -1.87